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Another US kids' swine flu vaccine recalled

Global swine flu deaths exceed 11,500: WHO
Geneva (AFP) Dec 23, 2009 - More than 11,500 people have died from swine flu worldwide since the pandemic strain was uncovered in April, World Health Organisation data showed Wednesday. The WHO said overall A(H1N1) influenza "activity has recently peaked in much of the (northern) hemisphere," including North America and western Europe, where the disease had surged in recent months with the onset of the colder season. "As of 20 December 2009, worldwide more than 208 countries and overseas territories or communities have reported laboratory confirmed cases of pandemic influenza H1N1 2009, including at least 11,516 deaths," the WHO said in its weekly update. "There continues to be increases in influenza activity in later affected areas of central and eastern Europe, and in parts of west, central, and south Asia," it added.
by Staff Writers
Washington (AFP) Dec 23, 2009
A week after 800,000 doses of children's swine flu vaccine were recalled in the United States for losing their potency, a second vaccine maker recalled its A(H1N1) nasal spray for the same reason.

MedImmune announced late Tuesday that it was "voluntarily recalling unused doses of 13 specific lots of influenza A(H1N1) 2009 Monovalent Vaccine Live, Intranasal due to a slight decrease in potency.

"There is no safety concern with the lots that are being recalled," it added in a statement.

The recall involves doses with best-before dates between January 19 and January 26, 2010.

MedImmune's nasal spray vaccine was the first to become available in the United States, but can only be administered to children older than two and healthy adults up to age 50.

According to Food and Drug Administration spokeswoman Karen Riley, the recall involves 3,000 doses of the nasal spray still at a central distribution center and an unknown number at healthcare facilities or with health care authorities in various states.

"Given the intense demand in October and November, we don't expect there is much left with healthcare facilities or in the states," said Riley.

Children and adults who had the nasal spray vaccine in the first months of the vaccination campaign in the United States do not need to be vaccinated again, MedImmune said.

Last week, Sanofi Pasteur recalled 800,000 doses of injectable swine flu vaccine for children after routine tests showed they had lost potency.

Like the MedImmune vaccine that was recalled Tuesday, Sanofi Pasteur said its treatment lost minimal strength and that children already inoculated with vaccine from the recalled lots would not require a second round of vaccinations.

New antiviral effective against bird flu
Madison, Wis. (UPI) Dec 23, 2009 - A compound tested in mice has proved safer and more effective against H5N1 bird flu than the popular antiviral Tamiflu, scientists in Wisconsin said.

T-705 even works after several days of infection, said Yoshihiro Kawaoka, a virologist at the University of Wisconsin's School of Veterinary Medicine.

"H5N1 virus is so pathogenic even Tamiflu doesn't protect all the infected animals," Kawaoka said. "This (antiviral) compound works much better, even three days after infection."

T-705 has been tested successfully against bird flu and H1N1 swine flu in mouse experiments and is being tested on humans in Japan against seasonal flu, Kawaoka said in the Proceedings of the National Academy of Sciences.

Some scientists believe bird flu, which is extremely difficult to treat, could spread worldwide, though so far cases have been isolated to Asia.

T-705 targets the viral molecule polymerase, an enzyme that enables the virus to copy its genetic material. By disabling polymerase, the virus can't create new virus particles needed to maintain the chain of infection, Kawaoka said in a release Tuesday.

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At least 60 million in US have had swine flu shot: CDC
Washington (AFP) Dec 22, 2009
At least 60 million people in the United States have been vaccinated against swine flu, and children are twice as likely as adults to have been innoculated, a top health official said Tuesday. "We think right now at least 60 million people have been vaccinated" against pandemic H1N1 flu, said Anne Schuchat from the US Centers for Disease Control and Prevention (CDC). Her findings were ... read more







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