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China grants emergency approval for its first Covid drug by AFP Staff Writers Beijing (AFP) Dec 9, 2021 China's drug authority has granted emergency approval for the country's first specialised treatment against Covid-19, found in clinical trials to significantly reduce hospitalisations and deaths among high-risk patients. The move comes as regulators around the world give the green light to treatments -- particularly for high-risk groups -- amid worries over the new Omicron variant. China is also grappling with a growing number of studies that show its vaccines have lower efficacy rates than many of those made overseas. In an official notice published Wednesday, China's National Medical Products Administration said it has granted "emergency approval" for a monoclonal antibody treatment. A monoclonal antibody is a type of protein that attaches to the spike protein of the coronavirus, reducing its ability to enter the body's cells. The treatment involves a combination of two drugs, administered through injections, and can be used to treat certain cases that are at risk of progressing in severity, the drug authority said. It was co-developed by Tsinghua University, the Third People's Hospital of Shenzhen and Brii Biosciences. Trial data showed that the combination therapy could reduce the risk of hospitalisation and death in high-risk patients by around 80 percent, Tsinghua University said in a statement on social media late Wednesday. A state media report last month added that the treatment has also been used on patients infected in local flare-ups. China is the latest to approve similar Covid-19 treatments, with British regulators last week also authorising an antibody treatment. EU health authorities have approved pills for emergency use too -- involving antiviral medications that slow down illness by reducing the virus's capacity to reproduce within the body. While pills are easier to use, the most effective treatment for Covid currently involves monoclonal antibodies, which are administered via a drip. China has several conditionally approved vaccines as well, but their published efficacy rates lag behind rival jabs developed in other countries. A study by Hong Kong's Chinese University published last month found people inoculated with the BioNTech vaccine had significantly higher antibody levels than China's Sinovac, adding to two other studies in Hong Kong and the mainland that produced similar data. The study did find the T-cell response -- white blood cells that remember how to fight disease -- remained strong in Sinovac patients. Hong Kong has begun calling for residents who were vaccinated with Sinovac to take a third booster to up their protection levels.
HIV infections drop, but Covid hampers fight: WHO Johannesburg (AFP) Dec 7, 2021 HIV infection rates in Africa have decreased markedly, but the continent is still behind set targets, with efforts slowed by the Covid-19 pandemic, the World Health Organization said Tuesday. "Africa has made significant progress against HIV over the past decade, reducing new infections by 43 percent and nearly halving AIDS-related deaths," the WHO Africa office said in a statement. But it warned that Africa was not likely to meet a target to end AIDS as a public health threat by the turn of the ... read more
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