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Chinese lab ready to soar with swine flu vaccine

Swine flu vaccine to cost up to 20 dollars per dose: WHO
Countries can expect to pay between 2.50 and 20 dollars for a dose of swine flu vaccine depending on their ability to meet the costs, a WHO official said in remarks published Wednesday. Marie-Paule Kieny, the head of vaccine research at the World Health Organisation, also warned that there would not be enough vaccines for the world's population and that people should not rely entirely on the vaccine. Rather, they should take other preventive measures against the A(H1N1) virus, such as avoiding large gatherings, closing schools and observing personal hygiene. "Coverage will be partial and not only in developing countries. But we should not be 'hypnotised' by vaccines," said Kieny in the interview published Wednesday in the WHO's Bulletin, a health journal. "There are other measures, such as social distancing, school closure, avoidance of large gatherings, antibiotics and personal hygiene. This is not like rabies, which is 100 percent fatal: we are talking about a disease from which most people recover very well," she added. Kieny reiterated that the WHO will help countries to get as much vaccine as possible, and that the wealthiest countries may have to pay up to 20 dollars. "The industry will use tiered pricing, so high-income countries might pay between 10 and 20 dollars per dose, middle-income countries may pay about half that and low-income half that price again," she said. "These are ballpark figures but this is the order of magnitude," she added. Britain and France have received their first batches of swine flu vaccine in late August, as governments began to arm themselves against an expected second wave of the pandemic in the northern winter. At least 2,185 people have died after contracting the swine flu virus which has overtaken other viruses to become the most prevalent flu strain.
by Staff Writers
Beijing (AFP) Sept 3, 2009
Up-and-coming Chinese biotech firm Sinovac, already listed in the United States, could get a significant boost abroad after securing government approval to produce its one-dose swine flu vaccine.

China's State Food and Drug Administration on Thursday gave the company the green light to make the vaccine, which has been shown in clinical trials to be effective against A(H1N1) influenza after just one shot.

"We have not found any negative side-effects -- it is safe and reliable," Sinovac president Yin Weidong told AFP in an interview ahead of the decision at his offices in Beijing's Zhongguancun district, or "China's Silicon Valley".

The company, which was founded in 2001, has been working feverishly since mid-June to produce the vaccine. In mid-August, it announced that the vaccine had performed well in trials conducted on more than 1,600 test subjects.

"We've taken advantage of our experience with bird flu in 2004, which has helped us to be ready and work quickly this time around, in terms of research and production," said the 45-year-old Yin.

The major advantage of the Sinovac vaccine, as compared with products made by major Western pharmaceuticals companies, would be the need for only one dose, resulting in both cost-effectiveness and a greater ability to stockpile.

"For a country as big as China, with such a huge population, this is an important asset," Yin explained.

Hans Troedsson, the outgoing representative of the World Health Organization (WHO) in China, told AFP that a one-dose vaccine would be "very important as it means we can vaccinate twice as many".

He also hailed China's efforts to quickly develop and produce a vaccine, given its status as the world's most populous nation with 1.3 billion inhabitants.

The SFDA said Thursday that it was considering applications from nine other Chinese companies seeking to produce A(H1N1) vaccines.

The WHO has warned of a possible swine flu vaccine shortage, as the winter -- and the regular flu season -- approaches in the northern hemisphere.

The government here plans to vaccinate 65 million people, or five percent of the population, before year's end.

Yin refused to speculate on the gravity of the global swine flu pandemic, or whether vaccinations are indeed the most reliable method of prevention.

"Everyone has his or her opinion on these matters, but my job is to carry out research on vaccines and produce them. I have to prepare for the worst," he said.

"If the worst were to happen, we would be ready to give the highest number of vaccinations in the shortest amount of time."

Yin and Sinovac are symbols of the emphasis China has placed on parlaying high-tech innovation into economic growth. The firm's efforts have not gone unnoticed -- President Hu Jintao and Premier Wen Jiabao have visited the lab.

The company contributed research to the 2003 global battle against Severe Acute Respiratory Syndrome (SARS), which killed about 800 people around the world, including 350 in China.

Yin said that experience has helped Sinovac position itself at the forefront of the campaign against swine flu, as its labs already adhere to international standards and his experts regularly confer with their peers abroad.

Sinovac has a total of 400 employees. A quarter of them are involved in research activities.

The company, which had sales of 20 million dollars in the first six months of 2009, up 21 percent from the same period a year ago, also hopes that success with a swine flu vaccine could boost its international profile.

"Most of our vaccines, about 90 percent of them, are sold in China. This is a chance for more countries to know about us and trust our products," Yin said.

Shuang Lewis, an analyst at IHS Global Insight, said Sinovac was "poised to see a major boost from this development".

"The company is also likely to benefit from this latest development in the longer term as there will be more opportunities for potential team-up with big pharmas" on vaccine development, Lewis said.

Sinovac's Yin says being the first company in China to mass-produce a vaccine makes no difference to him, as the fight against A(H1N1) "is not like the race for an Olympic gold medal".

"The most important thing is to protect as many people as possible," he said.

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Flu threat rules out election hugs and handshakes
Oslo (AFP) Sept 1, 2009
The threat of swine flu causing empty voting booths and bedridden politicians is being taken seriously ahead of Norway's general election this month. Politicians are trying to avoid hugs and handshakes and carry around disinfectant with them, while campaign workers wear throwaway gloves to give out free cups of coffee ahead of the September 14 vote. As pollsters predict a close race ... read more







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